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November 1, 2021Journal of the American College of Cardiology228 citationsOpen Access

Effect of β-Blocker Withdrawal on Functional Capacity in Heart Failure and Preserved Ejection Fraction

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PPPatricia PalauJSJulia SellerEDEloy Domínguez

Structured PICO

Does β-blocker withdrawal improve maximal functional capacity in patients with HFpEF and chronotropic incompetence?

P
Population
Patients with heart failure and preserved ejection fraction (HFpEF) and chronotropic incompetence
I
Intervention
β-blocker withdrawal
O
Outcome
Maximal functional capacitysurrogate

Withdrawal of β-blockers improves functional capacity in patients with HFpEF and chronotropic incompetence, suggesting their routine use in this population should be re-evaluated.

Abstract

β-blocker withdrawal improved maximal functional capacity in patients with HFpEF and chronotropic incompetence. β-blocker use in HFpEF deserves profound re-evaluation. (β-blockers Withdrawal in Patients With HFpEF and Chronotropic Incompetence: Effect on Functional Capacity PRESERVE-HR; NCT03871803; 2017-005077-39).

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Cite This Study

Palau et al. (2021) studied this question.

synapsesocial.com/papers/69de7cf9fd84e72eb25585c9https://doi.org/10.1016/j.jacc.2021.08.073
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