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January 31, 2020New England Journal of Medicine6,415 citationsOpen Access

First Case of 2019 Novel Coronavirus in the United States

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MHMichelle HolshueCDChas DeBoltSLScott Lindquist

Key Points

  • To report the first confirmed case of 2019-nCoV infection in the United States and analyze its clinical progression.
  • Case report of the first 2019-nCoV infection in the US.
  • Described clinical symptoms, diagnosis, and management of the patient.
  • Highlighted coordination among healthcare and public health authorities.
  • Initial mild symptoms progressed to pneumonia by day 9 of illness.
  • Rapid identification and management of the infection were emphasized.
  • Importance of information sharing among health authorities was highlighted.

Abstract

An outbreak of novel coronavirus (2019-nCoV) that began in Wuhan, China, has spread rapidly, with cases now confirmed in multiple countries. We report the first case of 2019-nCoV infection confirmed in the United States and describe the identification, diagnosis, clinical course, and management of the case, including the patient's initial mild symptoms at presentation with progression to pneumonia on day 9 of illness. This case highlights the importance of close coordination between clinicians and public health authorities at the local, state, and federal levels, as well as the need for rapid dissemination of clinical information related to the care of patients with this emerging infection.

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Cite This Study

Holshue et al. (2020) studied this question.

synapsesocial.com/papers/69deab65210a0977fce95202https://doi.org/10.1056/nejmoa2001191
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