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July 28, 2002Antimicrobial Agents and Chemotherapy447 citationsOpen Access

Hematologic Effects of Linezolid: Summary of Clinical Experience

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SGStanton L. GersonSKSheldon L. KaplanJBJon Bruss

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Abstract

Linezolid has been associated with reversible myelosuppression. Clinical trial data were evaluated for anemia, thrombocytopenia, and neutropenia. Thrombocytopenia and a slight increased risk for anemia were evident at > or =2 weeks of linezolid treatment. Hematologic abnormalities were consistent with mild, reversible, duration-dependent myelosuppression. Appropriate monitoring is warranted with linezolid use.

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Gerson et al. (2002) studied this question.

synapsesocial.com/papers/69deabb1afb501b9b65586bfhttps://doi.org/10.1128/aac.46.8.2723-2726.2002
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