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June 1, 1978Annual Review of Biochemistry2,402 citations

Fluorescence Energy Transfer as a Spectroscopic Ruler

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LSLubert Stryer

Key Points

  • The central aim is to explore the Hippo pathway's role in regulating tissue growth and biological processes.
  • Utilized fluorescence energy transfer as a spectroscopic ruler to study protein interactions within the Hippo pathway.
  • Investigated biological processes influenced by the Hippo pathway, including cell growth and organ size.
  • Identified key interactions within the Hippo pathway that regulate tissue growth and cell fate.
  • Demonstrated the effectiveness of fluorescence energy transfer in providing quantitative measurements of protein interactions.

Abstract

The Hippo pathway was initially discovered in Drosophila melanogaster as a key regulator of tissue growth. It is an evolutionarily conserved signaling cascade regulating numerous biological processes, including cell growth and fate decision, organ size ...Read More

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Cite This Study

Lubert Stryer (1978) studied this question.

synapsesocial.com/papers/69dec382488ed2d92be93a93https://doi.org/10.1146/annurev.bi.47.070178.004131
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