Does MR angiography quantitatively evaluate age-related tortuosity and hemodynamic alterations in carotid and vertebral arteries across the adult lifespan?
MR angiography provides quantitative reference ranges for age-related morphological and hemodynamic alterations in neck arteries across the adult lifespan.
Vascular auto-segmentation, centerline tracking, and phase mapping provide promising quantitative assessments of tortuosity and its effects on blood flow. The neck arteries demonstrate quantifiable and significant age-related morphological and hemodynamic alterations. Moreover, females showed more distinct vascular changes with age. Our work is built upon a comprehensive quantitative investigation of a large cohort of populations covering adult lifespan using MRI, the results can serve as reference ranges of each decade in the general population.
Sun et al. (2022) studied this question.