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May 26, 2006Arteriosclerosis Thrombosis and Vascular Biology168 citationsOpen Access

Childhood C-Reactive Protein in Predicting CRP and Carotid Intima-Media Thickness in Adulthood

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MJMarkus JuonalaJVJorma ViikariTRTapani Rönnemaa

Structured PICO

Do childhood C-Reactive Protein (CRP) levels predict adult CRP and carotid intima-media thickness?

P
Population
Children followed into adulthood
I
Intervention
Childhood C-Reactive Protein (CRP) levels
O
Outcome
Adult CRP and Carotid Intima-Media Thickness (IMT)surrogate

Childhood CRP is a weak independent predictor of adult CRP but does not predict adult carotid intima-media thickness, suggesting it may not be a strong early marker for structural vascular changes.

Abstract

Childhood CRP values predict weakly but significantly adult CRP, and this association is independent of other metabolic risk factors. Unlike conventional risk factors, however, childhood CRP does not predict adult IMT.

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Cite This Study

Juonala et al. (2006) studied this question.

synapsesocial.com/papers/69df23ecb8d7e94566614addhttps://doi.org/10.1161/01.atv.0000228818.11968.7a
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Interleukin-6 and the acute phase response1990 · 2,775 citations
  2. 2Long-Term Effects of Pravastatin on Plasma Concentration of C-reactive Protein1999 · 1,482 citations
  3. 3Tracking of blood lipids and blood pressures in school age children: the Muscatine study.1978 · 401 citations
  4. 4The Bogalusa Heart Study1991 · 1,330 citations
  5. 5C-reactive protein immunohistochemical localization in normal and atherosclerotic human aortas.1987 · 160 citations