PulseExploreJournal ClubDebatesTrendingResearchersJournals
Instagram
HomeExploreJournal ClubTrending
Synapse
⌘+K
Synapse
April 15, 2026Pathogens0 citationsOpen Access

Mesenchymal Stem Cell-Derived Extracellular Vesicles in Periodontal Disease

The Promise and Challenges of Mesenchymal Stem Cell-Derived Extracellular Vesicles in Periodontal Disease

View Full Paper
Ask AI
Bookmark
Share

Authors

JBJonghoe Byun

Discussion

Loading...

Member takes

Overview

Review maps the therapeutic potential of MSC-derived EVs for periodontal regeneration, suggesting clinical applications.

Key Points

  • This review aims to evaluate MSC-derived extracellular vesicles in periodontal regeneration and their associated challenges.
  • Conducted a comprehensive literature search on PubMed for studies on MSC-EVs and periodontitis.
  • Charted data regarding EV cargo composition and biological functions.
  • Analyzed regenerative outcomes and reported limitations of MSC-EVs.
  • MSC-EVs contain bioactive molecules that modulate immune responses and promote tissue repair.
  • In periodontal models, MSC-EVs reduce osteoclast activity and enhance fibroblast proliferation.
  • Evidence shows MSC-EVs stimulate extracellular matrix remodeling for periodontal regeneration.

Cite This Study

Jonghoe Byun (2026) studied this question.

synapsesocial.com/papers/69df2c77e4eeef8a2a6b18efhttps://doi.org/10.3390/pathogens15040420
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1New frontiers in salivary extracellular vesicles: transforming diagnostics, monitoring, and therapeutics in oral and systemic diseases2024 · 40 citations
  2. 2The Precision Paradigm in Periodontology: A Multilevel Framework for Tailored Diagnosis, Treatment, and Prevention2025 · 11 citations
  3. 3Prevalence and Socio-Behavioural Determinants of Periodontal Disease Among Adults in the Northern West Bank: A Cross-Sectional Study2026 · 2 citations
  4. 4Immunomodulatory properties of mesenchymal stem cells/dental stem cells and their therapeutic applications2023 · 254 citations
  5. 5The secretion profile of mesenchymal stem cells and potential applications in treating human diseases2022 · 734 citations