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April 15, 2026Pediatric Research1 citationsOpen Access

A novel urine collection device for accurate urinary measurements in neonates and pre-continent infants

SNS. H. M. NautaRadboud University NijmegenLCLieke A.E.A. CorbeekRadboud University NijmegenMBMiranda van Berkel

Key Points

  • The study aims to evaluate the accuracy of urinary component measurements using a new urine collection device for neonates and infants.
  • Developed a non-invasive urine collection device called the Specturi urine collector.
  • Incubated urine samples under varying conditions of duration, temperature, and humidity.
  • Analyzed urinary components, including calcium, magnesium, and pH, before and after incubation.
  • Assessed the effect of acidification on calcium concentration and crystal formation.
  • Accurate measurements for most urinary components were achieved, except for calcium in alkaline urine.
  • Minimal effect of incubation conditions on urinary measurements was observed.
  • Calcium, magnesium, and phosphorus crystals were detected on the textile with alkaline urines, but recovery of calcium was possible through acidification.
  • The new device proved to be more accurate than existing textile-based urine collection methods.

Abstract

Urine collection from neonates and infants is challenging. All available urine collection methods (UCMs) have their disadvantages, like invasiveness, contamination, and/or inaccurate measurements of urinary components. This study aimed to demonstrate the accuracy of measurements of urinary components for the novel non-invasive ‘Specturi urine collector device’. The urine collection textile was incubated under different conditions (incubation duration, temperature, and humidity) with either artificial or human urine. Concentrations of urinary components were compared before and after incubation. Because of suspected crystal formation, the effect of acidification was assessed in combination with crystal analysis. Urinary concentrations of calcium, magnesium, phosphate, sodium, creatinine, and protein, and pH were accurately measured, except for the calcium concentration in alkaline urines. The incubation conditions showed no to a small effect on the measurement of urinary components, which does not affect clinical decision-making. Crystals containing calcium, magnesium, and phosphorus formed on the textile after incubation with alkaline urine. Acidification recovered the calcium concentration in these urines. The non-invasive ‘Specturi urine collector device’ provides accurate measurements of urinary components under different conditions. This UCM is more accurate than other textile-based UCMs. Eventually, this device can be used as an accurate as well as patient- and staff-friendly UCM.

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Cite This Study

Nauta et al. (2026) studied this question.

synapsesocial.com/papers/69df2cb9e4eeef8a2a6b1eechttps://doi.org/10.1038/s41390-026-04891-y
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