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May 16, 2019JCO Precision Oncology50 citationsOpen Access

Crizotinib and Surgery for Long-Term Disease Control in Children and Adolescents With ALK-Positive Inflammatory Myofibroblastic Tumors

TTToby N. TrahairAGAndrew J. GiffordAFAshleigh M. Fordham

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Abstract

We confirm acceptable toxicity and excellent disease control in patients with AP-IMT treated with crizotinib, which may be ceased without recurrence in most. Relapses occurred in two of three patients with RANBP2-ALK translocated IMT, which suggests that such patients require additional therapy.

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Trahair et al. (2019) studied this question.

synapsesocial.com/papers/69df3e7544b0122c4f7a0f1ehttps://doi.org/10.1200/po.18.00297
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