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July 26, 2021Journal of Clinical Oncology613 citationsOpen Access

Acalabrutinib Versus Ibrutinib in Previously Treated Chronic Lymphocytic Leukemia: Results of the First Randomized Phase III Trial

JBJohn C. ByrdPHPeter HillmenPGPaolo Ghia

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Abstract

In this first direct comparison of less versus more selective Bruton's tyrosine kinase inhibitors in CLL, acalabrutinib demonstrated noninferior PFS with fewer cardiovascular adverse events.

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Byrd et al. (2021) studied this question.

synapsesocial.com/papers/69df6e4258b92af24d7a18eahttps://doi.org/10.1200/jco.21.01210
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