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November 4, 2016Anesthesia & Analgesia165 citations

Epidural Local Anesthetics Versus Opioid-Based Analgesic Regimens for Postoperative Gastrointestinal Paralysis, Vomiting, and Pain After Abdominal Surgery

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JGJoanne GuayMNMina NishimoriSKSandra L. Kopp

Structured PICO

Does an epidural containing a local anesthetic improve postoperative gastrointestinal transit and pain compared to opioid-based regimens in patients after abdominal surgery?

P
Population
Patients after abdominal surgery
I
Intervention
Epidural containing a local anesthetic, with or without an opioid
C
Comparator
Opioid-based analgesic regimens
O
Outcome
Postoperative gastrointestinal transit, vomiting, and pain

Epidural local anesthetics accelerate gastrointestinal transit and reduce pain after abdominal surgery compared to opioid-based regimens.

Abstract

An epidural containing a local anesthetic, with or without the addition of an opioid, accelerates the return of the gastrointestinal transit (high quality of evidence). An epidural containing a local anesthetic with an opioid decreases pain after an abdominal surgery (moderate quality of evidence). An epidural containing a local anesthetic does not affect the incidence of vomiting or anastomotic leak (low quality of evidence). For an open surgery, an epidural containing a local anesthetic would reduce the length of hospital stay (very low quality of evidence).

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Cite This Study

Guay et al. (2016) studied this question.

synapsesocial.com/papers/69e07add3dcc343e9cc11f1bhttps://doi.org/10.1213/ane.0000000000001628
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