Ectopic pancreas is usually asymptomatic but it may rarely cause gastric outlet obstruction when complicated by pancreatitis. We report two cases of ectopic pancreatitis in the gastric antrum, presenting with recurrent epigastric pain and vomiting. In the first case, imaging and Endoscopic ultrasound (EUS)-guided biopsy confirmed ectopic pancreas with chronic pancreatitis, and laparoscopic wedge resection resolved the symptoms. In the second case, ectopic pancreatitis with a pseudocyst was successfully managed with EUS-guided drainage, with no recurrence during the 3-year follow-up. Ectopic pancreatitis should be considered in the differential diagnosis of gastric outlet obstruction in young patients. Furthermore, the therapeutic strategy should be tailored to the characteristics of the lesion.
Jang et al. (2026) studied this question.