PulseExploreJournal ClubDebatesTrendingResearchersJournals
Instagram
HomeExploreJournal ClubTrending
Synapse
⌘+K
Synapse
April 16, 2026Movement Disorders0 citations

Diffusion Magnetic Resonance Imaging of Cortical Microstructure Differs in Nonmanifest and Manifest Genetic Parkinson's Disease

View Full Paper
MTMario TorsoDTDimitra TzaferouMVMichele Valotti

Key Points

  • The research investigates the role of cortical diffusivity metrics in identifying genetic Parkinson's disease stages.
  • Used diffusion magnetic resonance imaging (MRI) to assess cortical changes.
  • Compared cortical metrics between manifest and nonmanifest genetic Parkinson's disease cases.
  • Analyzed diffusivity metrics as potential neurodegenerative markers.
  • Cortical diffusivity metrics show significant differences between manifest and nonmanifest cases.
  • Findings support the use of these metrics as indicators of cortical architectural changes in genetic Parkinson's disease.

Abstract

Cortical diffusivity metrics effectively capture cortical architectural changes across clinical stages of genetic PD, supporting their use as microstructural markers of neurodegeneration in PD. © 2026 International Parkinson and Movement Disorder Society.

Ask AI
Helpful
Bookmark
Share
View Full Paper

Cite This Study

Torso et al. (2026) studied this question.

synapsesocial.com/papers/69e07c972f7e8953b7cbdcc5https://doi.org/10.1002/mds.70298
Ask AI
Helpful
Bookmark
Share
View Full Paper