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Synapse
April 16, 2026Acta Neuropsychiatrica0 citationsOpen Access

Immunological Predictors in First-Episode Psychosis: Findings from One Year Prospective Follow-Up Study

TSTalat SarıkavakÖÖÖzgür ÖzkalaycıASAytül Sin

Key Points

  • The study aims to identify immunological profiles that predict the onset and progression of first-episode psychosis (FEP).
  • Longitudinal design tracking immunological profiles over one year.
  • Assessment of innate and adaptive immunity contributions across illness phases.
  • Prospective follow-up of individuals experiencing their first episode of psychosis.
  • Distinct contributions of innate and adaptive immunity were observed throughout the illness phases.
  • Immunological profiles were found to be dynamic and associated with psychosis progression.

Abstract

This longitudinal study provides a system-level immunological profile across illness phases in FEP. The findings underscore distinct and dynamic contributions of innate and adaptive immunity to the onset and progression of psychosis.

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Cite This Study

Sarıkavak et al. (2026) studied this question.

synapsesocial.com/papers/69e07dc72f7e8953b7cbeb1dhttps://doi.org/10.1017/neu.2026.10076
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