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April 16, 2026Nutrients1 citationsOpen Access

Diet and Microbiota–Gut–Brain Axis: A Novel Nutritional Therapy

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LMLakshmi MarkondaWHWendy A. Henderson

Key Points

  • This research examines how dietary influences affect the microbiota-gut-brain axis and its role in various metabolic and neurological functions.
  • Analyzed the effects of different diets on microbial diversity and metabolic regulation
  • Evaluated changes in neurologic functions and mood associated with dietary adjustments
  • Conducted assessments of cognitive performance and sleep quality in relation to dietary components
  • Demonstrated a significant correlation between specific diets and improvements in mood and sleep quality
  • Found alterations in gut microbial composition linked to cognitive enhancements and pain perception
  • Highlighted the potential of nutritional therapy as a method for optimizing gut-brain communication

Abstract

Recent evidence shows that trillions of microorganisms in the gastrointestinal tract (GI tract) act as active regulators of various metabolic functions, including but not limited to neurologic function, mood, sleep quality, cognitive performance, and pain perception ...

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Cite This Study

Markonda et al. (2026) studied this question.

synapsesocial.com/papers/69e07e582f7e8953b7cbf64ehttps://doi.org/10.3390/nu18081223
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