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April 17, 2026International Urogynecology Journal2 citationsOpen Access

Association Between Intrapartum Papaverine Administration and the Risk of Obstetric Anal Sphincter Injuries: A Retrospective Cohort Study

RSRaneen Abu ShqaraNGNadir GanemAAAla Aiob

Key Points

  • To examine the association between intrapartum papaverine administration and the risk of obstetric anal sphincter injuries (OASIS).
  • Retrospective cohort study design
  • Analysis of primiparous patients
  • Comparison between those administered papaverine and those who were not
  • Lower incidence of OASIS observed in patients receiving intrapartum papaverine
  • Findings may indicate a protective effect of papaverine against anal sphincter injuries

Abstract

In this study, primiparous patients who received intrapartum papaverine experienced a lower incidence of OASIS than those who did not receive papaverine. Further prospective, protocolized studies are needed to confirm these findings.

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Cite This Study

Shqara et al. (2026) studied this question.

synapsesocial.com/papers/69e1cf7b5cdc762e9d8586e2https://doi.org/10.1007/s00192-026-06588-6
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