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April 17, 2026Open Access

Association Between Intrapartum Papaverine Administration and the Risk of Obstetric Anal Sphincter Injuries: A Retrospective Cohort Study

Key Points

To examine the association between intrapartum papaverine administration and the risk of obstetric anal sphincter injuries (OASIS).
Retrospective cohort study design
Analysis of primiparous patients
Comparison between those administered papaverine and those who were not
Lower incidence of OASIS observed in patients receiving intrapartum papaverine
Findings may indicate a protective effect of papaverine against anal sphincter injuries

Abstract

In this study, primiparous patients who received intrapartum papaverine experienced a lower incidence of OASIS than those who did not receive papaverine. Further prospective, protocolized studies are needed to confirm these findings.

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Shqara et al. (Wed,) studied this question.

synapsesocial.com/papers/69e1cf7b5cdc762e9d8586e2 https://doi.org/https://doi.org/10.1007/s00192-026-06588-6

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