April 18, 2026American Journal of Veterinary Research1 citationsOpen Access
Long-term sacubitril/valsartan is well tolerated in dogs with heart failure and myxomatous mitral valve disease and suggests excellent survival benefits
The study aims to evaluate the dosing schedule and clinical tolerance of sacubitril/valsartan in dogs with heart failure.
Evaluated the dosing schedule of sacubitril/valsartan in canine patients.
Assessed clinical tolerance over a long-term period.
Collected data to inform future studies.
Demonstrated that sacubitril/valsartan is well tolerated in dogs.
Indicated potential survival benefits in dogs with heart failure and myxomatous mitral valve disease.
Abstract
This study reports a dosing schedule and clinical tolerance of sacubitril/valsartan. It further provides important data for planning future prospective studies.