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April 18, 2026Arteriosclerosis Thrombosis and Vascular Biology0 citations

Orai1 Facilitates Angiogenesis After Myocardial Infarction Through Notch1 Signaling Pathway

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IGIsabel Galeano-OteroBDBeltzane Dominguez-ListeCACarlos Aspron

Key Points

  • This research aims to investigate how Orai1 contributes to angiogenesis following myocardial infarction (MI).
  • Examined the role of Orai1 in angiogenesis after myocardial infarction
  • Analyzed the involvement of Notch1 signaling pathway
  • Utilized experimental models to assess cardiac repair mechanisms
  • Orai1 was found to facilitate angiogenesis after MI
  • Notch1 signaling pathway was implicated in this process
  • Orai1 presents a potential target for therapies aimed at heart repair

Abstract

Together, these findings reveal a novel role for the Orai1-dependent mechanism in post-MI angiogenesis, highlighting Orai1 as a potential therapeutic target for cardiac repair.

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Cite This Study

Galeano-Otero et al. (2026) studied this question.

synapsesocial.com/papers/69e3201440886becb653f2afhttps://doi.org/10.1161/atvbaha.125.324231
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Also Consider

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