This research aims to develop a microneedle-based biosensor for measuring biomarkers related to dry eye disease.
Developed an electrochemical aptamer-based biosensor using microneedles.
Collected tear samples to analyze molecular biomarkers.
Executed quantitative measurement techniques for biomarker analysis.
Successfully collected and analyzed tear biomarkers using the biosensor.
Showed potential for high accuracy and reliability in measuring dry eye disease indicators.
Abstract
Dry eye disease (DED) is a prevalent ocular disorder driven by tear film instability and inflammation. The quantitative measurement of molecular biomarkers in tears can provide a reliable, and accurate...