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April 19, 2026Journal of Child Neurology0 citationsOpen Access

Paediatric Idiopathic Intracranial Hypertension in Wales: A Retrospective Observational Study

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RKRussell Azad KhanHSHuw StraffordBFBeata Fonferko‐Shadrach

Key Points

  • The study aims to measure the incidence and prevalence of idiopathic intracranial hypertension (IIH) in children and examine associated risk factors.
  • Conducted a retrospective observational study in Wales from 2003 to 2017.
  • Identified 177 children aged 1-15 with diagnosed IIH.
  • Analyzed incidence rates, risk factors related to BMI, and health care utilization.
  • Incidence of IIH increased from 1.6 to 3.5 per 100,000 per year between 2003 and 2017.
  • 63% of the diagnosed children were girls, mostly aged 7 to 15.
  • Obese children had a significantly higher odds ratio (OR = 21) for developing IIH.
  • Children in the most deprived quintile were 1.7 times more likely to develop IIH compared to those in the least deprived.
  • Children with IIH had 3.9 times higher hospital admission rates.

Abstract

This study measures the incidence and prevalence of idiopathic intracranial hypertension (IIH) in children in Wales and assesses risk factors and health care utilisation. We identified 177 children (1-15 years) with IIH diagnosed between 2003 and 2017. Incidence increased from 1.6/100 000 per year (2003) to 3.5/100 000 per year (2017). Sixty-three percent of the cases were girls, and 87% were diagnosed between 7 and 15 years. Children in the most deprived quintile were more likely to develop IIH compared to children in the least deprived quintile (odds ratio OR = 1.7 95%CI = 1.1-2.9). Obese and overweight children were more likely to develop IIH compared with non-overweight children (ORs = 21 95%CI = 9-51 and 5.1 95%CI = 1.9-14). Children with IIH had higher hospital admission rates than children without IIH (rate ratio = 3.9; 95% CI 3.6-4.3). The increasing incidence, association with BMI and deprivation, and increased health care utilisation in children with IIH are relevant findings to health care professionals and policy makers.

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Cite This Study

Khan et al. (2026) studied this question.

synapsesocial.com/papers/69e47376010ef96374d8f45fhttps://doi.org/10.1177/08830738261436139
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