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April 21, 20260 citations

Proteome-based identification and validation of NXPE3 in childhood acute lymphoblastic leukaemia.

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NTNajia TabassumZiauddin UniversityYKYamna KhurshidZiauddin UniversityBSBasir SyedChapman University

Key Points

  • This research aims to identify NXPE3's potential role as a biomarker in childhood acute lymphoblastic leukaemia (cALL).
  • Proteome-based identification of NXPE3 in childhood acute lymphoblastic leukaemia.
  • Assessment of NXPE3's potential in indicating CNS infiltration.
  • Exploration of NXPE3's role in leukemogenesis.
  • NXPE3 is identified as a potential biomarker for CNS infiltration in cALL.
  • Further investigation is suggested to elucidate its role in leukemogenesis.

Abstract

This is the first report of NXPE3 in cALL. NXPE3 was identified as a potential biomarker for assessing CNS infiltration in cALL. Further studies are recommended to explore its role in leukemogenesis.

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Cite This Study

Tabassum et al. (2026) studied this question.

synapsesocial.com/papers/69e71423cb99343efc98d75ehttps://doi.org/10.36721/pjps.2026.39.6.176.1
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Prognostic Value and Immune Characterization of Genes Associated with Childhood Acute Leukemia applying Single-Cell RNA Sequencing2025
  2. 2NEAT1 lncRNA overexpression results in short‐term progression and poor treatment outcome in childhood B‐ ALL2025
  3. 3PXDN, TCF4 and TSPAN7 Are Differentially Expressed in B-Cell Acute Lymphoblastic Leukaemia: An Integrative Analysis2026
  4. 4Long Non-Coding RNA RP11-252C15.1 Is a Potential Biomarker of Prognosis and Hallmark for Leukemogenesis in Children with B-Cell Precursor Acute Lymphoblastic Leukemia2024 · 2 citations
  5. 5Plasma proteome profiles of standard-risk and high-risk childhood acute lymphoblastic leukemia2026