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April 22, 2026Tanta Medical JournalOpen Access

Role of interleukin-17 level in assessment of disease activity in peripheral and axial spondyloarthritis and its relation to different methods of treatment

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Authors

SAShaimaa A. AbdelwahabNSNema A. SolimanDADina H.M. Abdella

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Overview

Case-control study investigates IL-17 levels and treatment effects on disease activity in spondyloarthritis, suggesting treatment implications.

Key Points

  • The study aims to examine the role of IL-17 levels in assessing disease activity in spondyloarthritis and its relationship with various treatments.
  • Conducted a case-control study with 40 participants divided into axial, peripheral, and both types of spondyloarthritis.
  • Participants received comprehensive clinical assessments and laboratory tests for IL-17 and C-reactive protein.
  • Analysis included disease activity measurements using established scales.
  • IL-17 levels were significantly higher in spondyloarthritis patients compared to healthy controls (P < 0.05).
  • Significant reduction in IL-17 and other disease activity scores was observed in peripheral spondyloarthritis compared to axial cases.
  • Treatment response differed, favoring biologic disease-modifying antirheumatic drugs in peripheral spondyloarthritis.

Cite This Study

Abdelwahab et al. (2026) studied this question.

synapsesocial.com/papers/69e866ad6e0dea528ddeb0echttps://doi.org/10.4103/tmj.tmj_91_25
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