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April 22, 2026Arthritis Care & Research0 citationsOpen Access

Obesity subtypes and longitudinal trajectories of function over 7‐years of follow‐up: data from the Multicenter Osteoarthritis Study

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KGKristine GodziukSTSarah TilleyMLMichael LaValley

Key Points

  • This research aims to examine how different obesity subtypes influence long-term mobility and function over seven years.
  • Analyzed data from the Multicenter Osteoarthritis Study
  • Compared functioning in individuals with different obesity subtypes over a 7-year follow-up period
  • Evaluated the impact of comorbidities on mobility outcomes
  • Individuals with obesity and low muscle or cardiometabolic comorbidities showed worse functioning over time
  • Those with obesity alone generally maintained better mobility
  • Early identification of obesity subtypes could facilitate personalized intervention strategies.

Abstract

Individuals with obesity and concurrent low muscle or cardiometabolic comorbidities have persistent worse functioning over a 7-year period compared to those with obesity alone. Distinguishing obesity subtypes may enable personalized interventions to delay or avoid extended mobility disability.

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Cite This Study

Godziuk et al. (2026) studied this question.

synapsesocial.com/papers/69e867356e0dea528ddeb776https://doi.org/10.1002/acr.80066
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

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  3. 3Elevated serum leptin levels are associated with low vitamin D, sarcopenic obesity, poor muscle strength, and physical performance in knee osteoarthritis2017 · 42 citations
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