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April 23, 2026Health Technology Assessment1 citationsOpen Access

A novel methodology using direct patient contact and UK national registries to collect long-term data from randomised trials: TARGIT-X – an extended follow-up study of the TARGIT-A trial of targeted intraoperative radiotherapy for breast cancer

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JVJayant S. VaidyaRoyal Free London NHS Foundation TrustNWNorman R WilliamsMBMax BulsaraThe University of Western Australia

Key Points

  • The aim is to develop a new way to gather long-term data from randomised trials for targeted intraoperative radiotherapy.
  • Utilized direct patient contact to enhance data collection.
  • Incorporated UK national registries for comprehensive data tracking.
  • Focused on long-term follow-up of patients from the TARGIT-A trial.
  • Generated robust long-term data on breast cancer treatment outcomes.
  • Improved data accuracy and completeness through patient engagement.
  • Enhanced understanding of targeted intraoperative radiotherapy effectiveness.

Abstract

This award was funded by the National Institute for Health and Care Research (NIHR) Health Technology Assessment programme (NIHR award ref: 14/49/13) and is published in full in Health Technology Assessment; Vol. 30, No. 29. See the NIHR Funding and Awards website for further award information.

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Cite This Study

Vaidya et al. (2025) studied this question.

synapsesocial.com/papers/69e9b80e85696592c86eb767https://doi.org/10.3310/gjjv2820
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