Research progress on the mechanisms of ovarian aging and interventions with kidney-tonifying formulas

Key Points

• This research integrates modern molecular mechanisms of ovarian aging and evaluates the clinical effects of kidney-tonifying formulas.
• Conducted a systematic literature review examining multiple aspects of ovarian aging.
• Evaluated clinical efficacy of kidney-tonifying formulas based on Traditional Chinese Medicine principles.
• Summarized basic research evidence on the regulatory effects of these formulas on key aging mechanisms.
• Identified several molecular mechanisms involved in ovarian aging, including oxidative stress and mitochondrial dysfunction.
• Found kidney-tonifying formulas positively impact ovarian reserve function and hormone levels.
• Provided basic research support for the multi-target, multi-pathway effects of these formulas on ovarian aging.