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April 23, 2026Lishizhen medicine and materia medica research0 citations

Clinical study on the intervention of italicQingxin Zishen Decoction/italic (清心滋肾汤) on pregnancy outcomes in patients with diminished ovarian reserve

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YWYixin WANGYZYuqing ZHANGAYAolan YANG

Key Points

  • This study aims to explore the effects of Qingxin Zishen Decoction on pregnancy outcomes in patients with diminished ovarian reserve using a traditional Chinese medicine system.
  • 150 patients with different constitutions were randomly divided into treatment and observational groups.
  • Treatment group received Qingxin Zishen Decoction in addition to conventional ovulation induction for 4 weeks.
  • Comparison of hormone levels and pregnancy rates was conducted before and after the intervention.
  • Patients in the treatment groups showed varying improvements in symptom scores related to their conditions.
  • Serum estradiol levels significantly increased in the yin-deficiency treatment group post-intervention.
  • Clinical pregnancy rates improved for both treatment groups compared to their observational counterparts.

Abstract

目的 基于中医体质辨识系统探讨清心滋肾汤干预卵巢储备功能减退患(dor)者妊娠结局的影响。 方法 选取150例阴虚质患者随机分为阴虚治疗组75例和阴虚观察组75例,选取150例气郁质患者随机分为气郁治疗组75例和气郁观察组75例。观察组采用常规促排卵治疗,治疗组在观察组基础上加服清心滋肾汤,疗程为4周,经期停服。分别比较治疗前后两组患者中医证候积分,血清基础促卵泡生成激素、促黄体生成素、雌二醇及抗缪勒管激素水平,窦卵泡数目,累及周期数,促性腺激素用量及促性腺激素天数,周期取消率,临床妊娠率、生化妊娠率、异位妊娠率、排卵率。 结果 阴虚质和气郁质患者服用清心滋肾汤后中医证候积分均得到不同程度的改善。阴虚质治疗组治疗后基础雌二醇水平较前明显上升;阴虚质和气郁质的治疗组在扳机日的雌二醇、促黄体生成素较观察组升高,a型子宫内膜形态的占比更高。阴虚质治疗组的临床妊娠率较观察组有一定改善;气郁质治疗组与观察组相比,在排卵率和临床妊娠率上体现出不同程度的优势。 结论 基于体质辨识系统观察清心滋肾汤干预卵巢储备功能减退患者妊娠结局具有积极意义,对治疗卵巢储备功能减退患者具有一定优势。

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Cite This Study

WANG et al. (2026) studied this question.

synapsesocial.com/papers/69e9bb9e85696592c86ed451https://doi.org/10.70976/j.1008-0805.szgygy-2026-0714
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Effect of acupuncture pretreatment on clinical pregnancy rate in women with diminished ovarian reserve undergoing IVF-ET: study protocol for a multicenter randomized controlled trial2026
  2. 2Effect of Tongyuan Acupuncture Combined With Qizi Yishen Lichong Decoction as Adjuvant Therapy for Infertility Caused by Premature Ovarian Insufficiency (Liver–Kidney Yin Deficiency Syndrome) and Its Influence on Patients’ Ovarian Reserve Function2026
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