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April 24, 2026The Journal of Pediatrics0 citationsOpen Access

Characterizing Barriers to Living Donor Liver Transplantation for Pediatric Recipients: Qualitative Results from the SOCIAL-Tx Study

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MKMorgan KellySASaba AliAHAndrea Huerta

Key Points

  • This research aims to identify barriers and facilitators affecting caregivers’ decisions about living donor liver transplantation for children with liver disease.
  • Conducted semi-structured interviews with caregivers of pediatric liver transplant recipients.
  • Analyzed qualitative data using coding by multiple reviewers guided by a behavioral framework.
  • Developed themes reflecting barriers to donor liver transplantation based on caregiver perspectives.
  • Half of participants reported low household incomes indicating economic barriers.
  • Identified seven key themes affecting decision-making, including time constraints, network limitations, and knowledge gaps.
  • Highlighted the need for strategies that support caregivers and enhance equitable access to transplantation.

Abstract

AbstractObjective To characterize barriers and facilitators influencing caregiver decision-making regarding living donor liver transplantation for children with end-stage liver disease. Study design This qualitative study used semi-structured, in-depth interviews conducted between May 2023 and March 2025 with caregivers of pediatric liver transplant recipients enrolled in the Social 50% reported household incomes Conclusions Strategies to support decision making about living donor liver transplantation should include counseling about the procedure's benefits early in the transplant evaluation process, helping identify non-directed donors and reducing the caregiving burden during the donor recovery period. Such efforts should prioritize under-resourced families to enhance equitable outcomes for children with end-stage liver disease.

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Cite This Study

Kelly et al. (2026) studied this question.

synapsesocial.com/papers/69eb084f553a5433e34b3571https://doi.org/10.1016/j.jpeds.2026.115112
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