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April 24, 2026Graefe s Archive for Clinical and Experimental Ophthalmology0 citationsOpen Access

Charles Bonnet syndrome in patients referred for cataract surgery

MNMads Assenholt NielsenJBJakob BjeragerGCGülsenay Citirak

Key Points

  • The study aims to evaluate the prevalence of Charles Bonnet Syndrome (CBS) among cataract surgery patients and identify associated factors.
  • Analyzed data from patients referred for cataract surgery
  • Conducted multivariable logistic regression to determine predictors of CBS
  • Monitored visual acuity and ocular comorbidities in participants
  • CBS was identified in 2.8% of cataract surgery patients
  • Prevalence of complex visual hallucinations rose to 10.0% with specific visual acuity criteria
  • 27.3% of CBS patients had ocular comorbidities like age-related macular degeneration

Abstract

Nineteen (4.9%) patients experienced complex VHs. Of these, 11 (2.8%) were diagnosed with CBS while 8 (2.1%) had complex hypnagogic and/or hypnopompic VHs. Multivariable logistic regression analysis identified lower best-corrected visual acuity (BCVA) in the better seeing eye as a significant predictor of CBS. When excluding participants with a BCVA>0.3, prevalence of complex VHs rose to 10.0%. Three of the patients with CBS (27.3%) had ocular comorbidities: two had exudative age-related macular degeneration (AMD), and one had drusenoid AMD. In the overall cohort, twenty-four patients (6.1%) reported prior knowledge of CBS. CONCLUSION: CBS was observed in a clinically relevant minority of cataract patients requiring bilateral surgical intervention. Given the high prevalence of cataract among the elderly, this study highlights the importance of healthcare personnel being aware of CBS and other complex VHs and their potential consequences for cataract patients.

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Cite This Study

Nielsen et al. (2026) studied this question.

synapsesocial.com/papers/69eb099a553a5433e34b3fc4https://doi.org/10.1007/s00417-026-07241-0
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