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April 25, 2026Organic & Biomolecular Chemistry0 citations

Synthesis of 2-aminobenzothiazole substituted indole via DBU catalyzed addition of indole and benzothiazolimine

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XSXiangjia SongYWYa-Xiong WangXGXin-Sheng Geng

Key Points

  • The aim is to synthesize 2-aminobenzothiazole substituted indoles using a DBU-catalyzed reaction.
  • Developed a DBU-catalyzed Mannich reaction between indoles and benzothiazolimines.
  • Utilized mild conditions to enhance efficiency and practicality.
  • Focused on pharmaceutical applicability of synthesized compounds.
  • Successfully synthesized a series of 2-aminobenzothiazole substituted indoles.
  • Demonstrated efficiency of the reaction process under mild conditions.

Abstract

A DBU-catalyzed Mannich reaction between indoles and benzothiazolimines has been developed, providing an efficient and practical approach to a series of 2-aminobenzothiazole substituted indoles with potential pharmaceutical relevance. Under mild...

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Cite This Study

Song et al. (2025) studied this question.

synapsesocial.com/papers/69ec5a2588ba6daa22dabadahttps://doi.org/10.1039/d6ob00152a
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