Is insulin resistance associated with impaired cardiovascular function and exercise capacity in youth with Type 1 Diabetes?
Youth with Type 1 diabetes exhibit a unique phenotype of insulin resistance that is associated with impaired exercise capacity and cardiovascular dysfunction.
T1D youth demonstrated IR, impaired functional exercise capacity and cardiovascular dysfunction. The phenotype of IR in T1D youth was unique, suggesting a pathophysiology that is different from T2D, yet may adversely affect long-term cardiovascular outcomes.
Nadeau et al. (2009) studied this question.