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June 30, 2025EP Europace18 citationsOpen Access

Esophageal endoscopic findings after pulmonary vein and posterior wall isolation using pulsed field ablation: results from the Eso-PFA study

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MGMelanie GunawardeneMMMelissa E. MiddeldorpUPUlrich‐Frank Pape

Structured PICO

Does pulsed field ablation for pulmonary vein and posterior wall isolation cause esophageal thermal injury in patients with atrial fibrillation?

P
Population
Patients undergoing atrial fibrillation ablation (pulmonary vein and posterior wall isolation)
I
Intervention
Pulsed field ablation (PFA) for left atrial posterior wall isolation (LAPWI) and pulmonary vein isolation
O
Outcome
Esophageal thermal injury assessed by post-procedural endoscopysafety

Pulsed field ablation for pulmonary vein and posterior wall isolation appears safe for the esophagus, with no thermal injury observed on post-procedural endoscopy.

Abstract

In this real-world cohort, PFA-guided LAPWI was safe for the esophagus, with no thermal injury observed in post-procedural endoscopy. These results further support PFA as a promising technology for AF ablation with a favourable esophageal safety profile. The role of post-ablation proton pump inhibitors in a population where incidental gastrointestinal findings were common needs further exploration.

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Cite This Study

Gunawardene et al. (2025) studied this question.

synapsesocial.com/papers/69eee0530fb71af24d311af1https://doi.org/10.1093/europace/euaf133
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