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April 27, 2026Physics in Medicine and Biology0 citationsOpen Access

A delta-based multi-omics model to predict adaptive radiotherapy benefit in patients with non-small cell lung cancer during carbon-ion radiotherapy

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ZJZhuojun JuNKNobuteru KuboXMXiangdi Meng

Key Points

  • The aim is to develop a delta-omic model to predict the demand for adaptive radiotherapy (ART) in patients with non-small cell lung cancer (NSCLC) undergoing carbon-ion radiotherapy (CIRT).
  • Developed a delta-omic model
  • Assessed ART demand in NSCLC patients
  • Highlighted the need for prospective validation in larger cohorts
  • The delta-omic model may optimize resource allocation for ART workflows.
  • Prospective validation is needed for wider clinical application.

Abstract

A delta-omic model predicting ART demand in patients with NSCLC receiving CIRT was developed. The model may help optimize resource allocation and streamline ART workflows, although prospective validation in larger cohorts is warranted before widespread clinical adoption.

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Cite This Study

Ju et al. (2026) studied this question.

synapsesocial.com/papers/69eefcaefede9185760d3931https://doi.org/10.1088/1361-6560/ae64a6
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