Does chronic vagus nerve stimulation improve quality of life and LV function safely in patients with chronic heart failure and severe systolic dysfunction?
Chronic vagus nerve stimulation appears to be a safe and tolerable novel therapeutic approach that may improve quality of life and LV function in patients with severe systolic heart failure, warranting further controlled trials.
This open-label study shows that chronic VNS in CHF patients with severe systolic dysfunction may be safe and tolerable and may improve quality of life and LV function. A controlled clinical trial appears warranted.
Ferrari et al. (2010) studied this question.