Hypoxic stress induces IL-6 production in cardiac myocytes, highlighting a potential mechanism for myocardial dysfunction in ischemia-reperfusion injury.
Cardiac myocytes respond to hypoxic stress to augment the production of IL-6, and the IL-6 derived from cardiac myocytes may play an important role in the progression of myocardial dysfunction observed in cardiac ischemia-reperfusion injury.
Yamauchi‐Takihara et al. (1995) studied this question.