Does contact panoramic mapping identify stable sources for human atrial fibrillation better than electrogram morphology?
Contact panoramic mapping, unlike electrogram morphology, can identify stable sources for human atrial fibrillation, suggesting that most CFAE sites are remote from AF sources and are not suitable targets for catheter ablation.
Stable rotors and focal sources for human AF were revealed by contact panoramic mapping (focal impulse and rotor modulation mapping), but not by electrogram footprints. AF sources precessed within areas of ≈2 cm(2), with diverse voltage characteristics poorly correlated with CFAE. Most CFAE sites lie remote from AF sources and are not suitable targets for catheter ablation of AF.
Narayan et al. (2013) studied this question.