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April 28, 2026American Journal of Neuroradiology0 citationsOpen Access

Tractography-based Predictors of Post-Stroke Aphasia: A Systematic Review

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MNMahshad NarimaniIKIman KianiHGHamed Ghorani

Key Points

  • This research aims to identify the structural predictors of post-stroke aphasia using tractography techniques.
  • Conducted a systematic review of existing studies on tractography and post-stroke aphasia.
  • Focused on the role of the arcuate fasciculus in predicting aphasia outcomes.
  • Emphasized the need for standardization and multicenter studies for clinical application.
  • Identified the arcuate fasciculus as the most consistent predictor of post-stroke aphasia.
  • Highlighted the necessity for standardized tractography protocols to improve diagnostic accuracy.
  • Recognized the gap in multicenter validation for clinical implementation.

Abstract

Tractography provides valuable insights into the structural substrates of post-stroke aphasia, with the arcuate fasciculus emerging as the most robust predictor. Standardization of tractography protocols and multicenter validation are needed before routine clinical translation.

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Cite This Study

Narimani et al. (2026) studied this question.

synapsesocial.com/papers/69f04e08727298f751e72057https://doi.org/10.3174/ajnr.a9333
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