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April 28, 2026Discover Oncology0 citationsOpen Access

Right breast invasive carcinoma and contralateral left axillary abscess representing a rare dual pathology

SASrilakshminagasaikrishnapraneeth AddagarlaARAshok RanjanKSKirthi Sathyakumar

Key Points

  • This case highlights the rare coexistence of right breast invasive carcinoma and left axillary abscess due to tuberculosis.
  • Patient presented with bilateral breast enlargement and palpable mass in left axilla.
  • Contrast-enhanced MRI and targeted ultrasound were performed, followed by FNAC for diagnosis.
  • Histopathological examination was conducted post-surgery.
  • FNAC confirmed invasive carcinoma in the right breast and an abscess in the left axilla.
  • CBNAAT detected Mycobacterium tuberculosis without resistance to rifampicin.
  • Histopathology revealed Grade 3 invasive carcinoma of no special type.

Abstract

A 53-year-old female patient complained of bilateral breast enlargement with a palpable mass in the left axilla. Contrast-enhanced MRI revealed a suspicious lesion in right breast along with an ill-defined collection in the left axilla. Targeted ultrasound revealed an irregular hypoechoic lesion in the right breast along with collections in the left axilla. FNAC of the lesion in right breast revealed invasive carcinoma, while FNAC of the left axillary swelling yielded purulent material suggesting abscess. Cartridge-based nucleic acid amplification testing (CBNAAT) detected the presence of Mycobacterium tuberculosis complex DNA without resistance to rifampicin. The patient was then given antitubercular treatment. The patient then underwent a wide local excision of the suspicious lesion in the right breast. The histopathological examination revealed Grade 3 invasive carcinoma of no special type (NST). This is a rare case of the coexistence of breast carcinoma along with contralateral tuberculous axillary lymphadenitis, which clinically mimicked metastatic axillary lymphadenopathy. The clinical, radiological and pathological correlation is essential to avoid any misdiagnosis of the tumor.

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Cite This Study

Addagarla et al. (2026) studied this question.

synapsesocial.com/papers/69f04e08727298f751e72115https://doi.org/10.1007/s12672-026-05072-3
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