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May 1, 20260 citations

Unveiling the Neuroprotective Role of Nutritional Supplements in Neurodegenerative Diseases.

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SSSonia Singh

Key Points

  • The aim is to explore the neuroprotective role of nutraceuticals in treating neurodegenerative diseases.
  • Data collected from sources including Scopus, Science Direct, Web of Science, and PubMed.
  • Examined various nutraceuticals and their mechanisms of action in neurodegenerative conditions.
  • Discussed the potential of nutraceuticals to avoid neuronal cell death and restore neuronal function.
  • Nutraceuticals show significant promise as neuroprotective agents in neurodegenerative diseases.
  • Current evidence is insufficient to recommend nutraceuticals in clinical guidelines for dementia.
  • Call for more high-level evidence studies to validate the use of nutraceuticals in neuroprotection.

Abstract

Nutraceuticals obtained from natural sources have been explored as well as studied for significant applications to treat several diseases like diabetes, cardiovascular diseases, and neurodegenerative diseases. The manuscript explores the mode of actions and different nutraceuticals used to treat various neurodegenerative disorders (NDs). The data have been extensively collected from various sources such as Scopus, Science Direct, Web of Science, and PubMed, respectively. Progressive malfunction and loss of neuronal structure as well as function, leading to neuronal cell death, are characteristic of ND conditions. Targeting various neuroprotection strategie avoiding cell death and restoring the function of damaged neurons, may be potential treatments for ND disorders. The application of nutraceuticals as neuroprotective agents in the treatment of ND disorders is a growing field of research. This article summarises the current knowledge regarding the neuroprotective effects of nutraceuticals against the pathologies of ND conditions. There is no way to recommend nutraceuticals in dementia-related therapy guidelines because of the severe scarcity of high-level evidence studies. However, more research is needed because of their promising neuroprotective action potential.

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Cite This Study

Sonia Singh (2025) studied this question.

synapsesocial.com/papers/69f443cb967e944ac5566dffhttps://doi.org/10.2174/0118715249389608251108031453
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