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Synapse
May 2, 20260 citations

Imprinted Arousal Pattern (IAP): A Transdiagnostic Clinical Reasoning for Compulsive Behaviors.

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RZRaymond Zakhari

Key Points

  • This paper aims to provide a clinically operational explanation for the recurrence of compulsive behaviors triggered by stress. It introduces the Imprinted Arousal Pattern (IAP) framework as a transdiagnostic model.
  • Proposes the IAP framework to conceptualize compulsive behaviors as conditioned loops of arousal, affect, meaning, and behavior.
  • Draws from various fields including addiction science, attachment research, and trauma-informed neurobiology.
  • Maps the IAP framework onto the Research Domain Criteria (RDoC) domains.
  • IAP reframes compulsive behaviors as learned regulatory systems that were once adaptive but have become rigid across varied contexts.
  • The framework explains the intolerance of low-arousal states and predictable stress-reactive relapses.
  • It suggests practical assessment and treatment considerations for psychiatric-mental health nursing practitioners.

Abstract

OBJECTIVE: (DSM-5-TR) provides descriptive reliability and the Research Domain Criteria (RDoC) framework advances dimensional neurobiological insight, neither alone offers a clinically operational explanation for stress-triggered recurrence. METHODS: This discussion paper proposes the Imprinted Arousal Pattern (IAP) framework, a transdiagnostic clinical reasoning model conceptualizing compulsive behaviors as conditioned arousal-affect-meaning-behavior loops consolidated through reinforcement and stress sensitization. The framework draws from addiction science, conditioning theory, attachment research, and trauma-informed neurobiology and is mapped onto RDoC domains. RESULTS: IAP reframes compulsive behaviors as learned regulatory architectures-once adaptive solutions for managing threat, shame, or dysregulation, now rigid and self-perpetuating across contexts. The framework provides a structured explanation for intolerance of low-arousal states and predictable stress-reactive relapse and translates into practical assessment and treatment considerations for psychiatric-mental health nurse practitioners. CONCLUSIONS: By shifting focus from symptom suppression to restructuring maladaptive regulatory systems, IAP offers a coherent, dignity-preserving formulation for compulsive behaviors. As a portable explanatory framework, it provides structured language for patterns long recognized in psychiatric nursing practice but insufficiently named.

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Cite This Study

Raymond Zakhari (2026) studied this question.

synapsesocial.com/papers/69f594ca71405d493afffaeehttps://doi.org/10.1177/10783903261443980
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