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June 6, 2011Angewandte Chemie International Edition270 citations

Fast Multidimensional NMR Spectroscopy Using Compressed Sensing

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DHDaniel J. HollandMBMark J. BostockLGLynn F. Gladden

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Abstract

Make it snappy! The use of compressed sensing to reconstruct multidimensional NMR spectra enables significant reductions in recording time. Thus, 3D HNCA (blue) and HN(CO)CA spectra (green) of sufficient quality for rapid protein-backbone assignment were reconstructed from only 16 % of the fully sampled data. The generality of the method and its robustness to noise should make it more broadly applicable, for example, to solid-state NMR spectroscopy. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.

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Cite This Study

Holland et al. (2011) studied this question.

synapsesocial.com/papers/69f652c9edbe0a7967afc36ahttps://doi.org/10.1002/anie.201100440
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