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Synapse
May 3, 20260 citations

Development and Pilot Clinical Study of a Novel FAP-Targeted PET Tracer for PET Imaging of Tumors.

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KCKeyin ChenRZRongqin ZhangXZXi Zhang

Key Points

  • This study aims to evaluate a new PET tracer targeting FAP for better imaging of tumors.
  • Pilot clinical study conducted to test the novel tracer F]AlF-AA-FAPT.
  • Comparison made with current FAPI tracers to assess improvements in imaging properties.
  • F]AlF-AA-FAPT shows an excellent target-to-background ratio compared to existing tracers.
  • Demonstrates improved pharmacokinetic properties over current FAPI options.

Abstract

F]AlF-AA-FAPT demonstrates excellent target-to-background ratio and improves pharmacokinetic properties, making it an effective alternative to current FAPI tracers.

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Cite This Study

Chen et al. (2026) studied this question.

synapsesocial.com/papers/69f6e5cf8071d4f1bdfc66bahttps://doi.org/10.1021/acs.analchem.5c07388
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