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March 15, 1995Circulation

The 115-J biphasic pulse, 130-J biphasic pulse, and 200-J damped sine wave pulse were equally effective, all resulting in a 97% first-shock ventricular defibrillation efficacy rate.

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Why the study?

Do low-energy biphasic truncated waveforms (115 J and 130 J) provide similar transthoracic defibrillation efficacy compared to standard 200-J damped sine wave pulses in cardiac arrest survivors?

Population

30 cardiac arrest survivors undergoing transvenous ICD surgery, mean age 61 +/- 11 years, 73% men. Mean LVEF…

Comparison

Low-energy biphasic truncated waveforms… vs Standard 200-J damped sine wave pulse.

Design

RCT, Each of the three different rescue shocks was tested in random order in…

Authors

GBGust H. BardyBGBradford E. GlinerPKPeter J. Kudenchuk

Discussion

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Overview

Supports compact AED development; confirms low-energy biphasic equivalence to damped sine wave in RCT.

Structured PICO

Do low-energy biphasic truncated waveforms (115 J and 130 J) provide similar transthoracic defibrillation efficacy compared to standard 200-J damped sine wave pulses in cardiac arrest survivors?

P
Population
30 cardiac arrest survivors undergoing transvenous ICD surgery, mean age 61 +/- 11 years, 73% men. Mean LVEF 0.39 +/- 0.14, coronary artery disease present in 73%.
I
Intervention
Low-energy biphasic truncated waveforms (115 J [70 microF] and 130 J [105 microF]) delivered via right anterior and left lateral thoracic pads.
C
Comparator
Standard 200-J (36-microF, 28-mH) damped sine wave pulse.
O
Outcome
First-shock ventricular defibrillation efficacy rate.

Low-energy biphasic truncated shocks (115 J and 130 J) are as effective as standard 200-J damped sine wave shocks for transthoracic defibrillation, supporting the development of smaller, more affordable AEDs.

Cite This Study

Bardy et al. (1995) studied this question.

synapsesocial.com/papers/69f6f1afbc46ec1a8b7c64f6https://doi.org/10.1161/01.cir.91.6.1768
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