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March 15, 2022SHILAP Revista de lepidopterología33 citationsOpen Access

CCL18 promotes breast cancer progression by exosomal miR-760 activation of ARF6/Src/PI3K/Akt pathway

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XHXiaojia HuangSLShengqing LaiFQFanli Qu

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Abstract

, migration, invasion, and chemoresistance by activating ARF6-mediated Src/PI3K/Akt signaling and the epithelial-mesenchymal transition (EMT) pathway. Together, our results support that exosomal miR-760 secreted by CCL18-stimulated high metastatic BC cells promoted the malignant behaviors in low metastatic BC cells by up-regulating the ARF6-mediated Src/PI3K/Akt signaling pathway.

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Cite This Study

Huang et al. (2022) studied this question.

synapsesocial.com/papers/69f8f4e5735fe9d1c179a049https://doi.org/10.1016/j.omto.2022.03.004
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