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May 6, 20260 citations

Photoexcited zinc oxide nanoparticles induce acute toxicity in Aedes aegypti larvae.

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SBSiti Khadijah Mohd BakhoriSMShahrom MahmudSHSiti Nasuha Hamzah

Key Points

  • This research explores the toxicity of zinc oxide nanoparticles on Aedes aegypti larvae and their mode of action.
  • Used photoexcited zinc oxide nanoparticles for testing
  • Analyzed acute toxicity in Aedes aegypti larvae
  • Examined mechanisms of toxicity including membrane disruption and ionic effects
  • Evaluated the role of size and surface area in toxicity levels
  • Zinc oxide nanoparticles demonstrated significant acute toxicity in larvae
  • Enhanced toxicity linked to smaller size and larger surface area
  • Findings indicate membrane disruption as a critical mechanism
  • Demonstrated potential for zinc oxide nanoparticles as effective larvicidal agents

Abstract

ions that cause membrane disruption and internal tissue damage. The enhanced toxicity of ZnO-C1 is attributed to its smaller size, larger surface area, and improved dispersion stability, which facilitate greater ROS generation and ionic dissolution. These findings demonstrate a distinct UV-dependent mode of action and highlight the potential of nanoscale ZnO as a photoactivated larvicidal agent against Ae. aegypti.

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Cite This Study

Bakhori et al. (2026) studied this question.

synapsesocial.com/papers/69fa8eac04f884e66b5310a3https://doi.org/10.1016/j.cbpc.2026.110557
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