OBJECTIVES: Assess the distribution of oral HPV genotypes and examine their associations with age and HIV-related factors among men living with HIV. METHODS: on oral gargles. Demographics and HIV-related characteristics were collected via questionnaires, and clinical assessments were conducted. ANOVA and chi-square tests assessed associations with age groups and HPV infection. RESULTS: Among 700 participants, oral HPV was detected in 27.9%, with HR-HPV detection at 11.0%. 4vHPV and 9vHPV types were detected in 4.9% and 8.9% participants, respectively. The most detected HR-HPV types were HPV 16 (2.4%), HPV 33 (2.0%), and HPV 52 (2.0%). No significant age-specific differences in oral HPV detected were observed. Higher detection rates of any HPV and HR-HPV were observed among participants with baseline CD4 counts below 200 cells/mm³ or a history of AIDS-defining conditions. CONCLUSIONS: Oral HPV genotyping in men with HIV reveals distinct oncogenic patterns, underscoring the need to monitor long-term OPSCC risk.
Beltrame et al. (2026) studied this question.