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May 6, 2026Dalton Transactions0 citations

Structurally characterized Ni(II) complex exhibiting potent anti-Candida activity: Biomolecular interaction mechanism and in silico ADMET insights

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ASAlipe SahaRMRibhu MaityGDGurupada Dhara

Key Points

  • The study aims to evaluate a Ni(II) Schiff base complex for its antifungal activity against Candida albicans and its associated biomolecular interactions.
  • Synthesis and structural characterization of Ni(II) Schiff base complex
  • Assessment of antifungal activity against Candida albicans
  • Analysis of biomolecular interactions and in silico ADMET properties
  • Ni(II) complex demonstrated potent anti-Candida activity
  • Biomolecular interactions indicated potential mechanisms of action
  • In silico ADMET analysis provided insights into drug-like properties

Abstract

The current study reports the synthesis, structural interpretation, biomolecular interaction, and antifungal appraisal of a Ni(II) Schiff base complex demonstrating effective activity against Candida albicans. The complex, formulated as Ni(L)₂,...

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Cite This Study

Saha et al. (2026) studied this question.

synapsesocial.com/papers/69faa1eb04f884e66b532959https://doi.org/10.1039/d6dt00455e
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