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May 6, 2026Circulation0 citations

Abstract TH945: The Weight of Stress: Examining the Association Between Perceived Stress and Body Mass Index (BMI) in The EPIPHANY (Equity in Prevention and Progression of Hypertension by Addressing barriers to Nutrition and Physical Activity) Study

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MMMiriam MilesLHLanisha HallKFKathryn Foti

Key Result

Moderate to high perceived stress was associated with a 12% to 15% higher prevalence of overweight or obesity among Black men compared to low stress, though not statistically significant.

Key Points

  • This work aims to evaluate the relationship between psychosocial stress and body mass index (BMI) among Black adults in rural Alabama.
  • Analyzed baseline data from 344 Black adults, aged 19 or older, from the EPIPHANY study.
  • Assessed psychosocial stress using the Perceived Stress Scale (PSS-4) and calculated BMI based on weight and height measurements.
  • Adjusted prevalence ratios (PR) were calculated to explore the association between stress levels and overweight/obesity, adjusting for social determinants and health behaviors.
  • Men with higher stress levels showed a 12% to 15% increased likelihood of being overweight/obese compared to those with lower stress scores, though results were not statistically significant.
  • Over 80% of both women and men reporting higher stress had overweight/obesity, indicating potential public health concerns despite not reaching statistical significance.

Study Design

Type

Cross-Sectional (n=344)

Structured PICO

Does moderate/high perceived stress associate with a higher prevalence of overweight/obesity in Black adults in rural communities?

P
Population
344 Black adults, ≥19 years older from the Black Belt area in Alabama from the EPIPHANY study, mean age 41.4 years, 68.0% women.
I
Intervention
Moderate/high perceived stress (PSS-4 scores 6-16)
C
Comparator
Low perceived stress (PSS-4 scores 0-5)
O
Outcome
Overweight/obesity (BMI > 25 kg/m2)surrogate

There was no statistically significant association between higher perceived stress and overweight/obesity among Black adults in rural Alabama.

Main Result

Effect estimate: PR 1.12-1.15

Absolute Event Rate: 84.4% vs 76.9%

p-value: p=not statistically significant

Abstract

Background: Black adults in rural areas have higher obesity prevalence (48. 3%), lower socioeconomic status, and decreased access to health services contributors to poor cardiovascular health. Further, stress among Black adults have been associated with higher BMI. This work examines whether psychosocial stress is associated with higher BMI among Black adults in rural communities. Methods: Baseline data from 344 Black adults, ≥19 years older from the Black Belt area in Alabama fromthe EPIPHANY study (a multilevel lifestyle intervention trial to reduce systolic blood pressure SBP). Psychosocial stress was assessed using the Perceived Stress Scale (PSS-4). Total PSS-4 score was calculated, and participants were grouped into low (scores 0-5) and moderate/high (scores 6-10 and 11-16, respectively) by sex. Weight and height were measured to calculate BMI. BMI was categorized as 25 kg/m 2 (overweight/obese). Adjusted prevalence ratios (PR) were calculated to evaluate the association between stress and overweight/obesity, by sex, adjusting for social determinants of health (Model 1), health behaviors (Model 2) and initial systolic and diastolic blood pressure (Model 3). Results: The mean age of participants was 41. 4 (13. 1) years and 68. 0% were women. Men and women reporting higher stress were more likely to earn <30, 000 annually and reported higher levels of depression (15%, p=0. 003 and 35. 2%, p<0. 001, respectively). Among women, those reporting higher stress were more likely to be younger (39. 6 vs 43. 9 years, p=0. 014) and delay healthcare due to cost (29. 7% vs 6. 4%, p < 0. 001) vs those reporting lower stress. Men reporting higher stress were significantly more likely to be current smokers (40. 0%, p=0. 022) vs those reporting low stress. Men had higher prevalence of obesity in lower and moderate/high stress (76. 9% and 84. 4%, respectively (Figure 1). Multivariable adjusted PR found men with higher stress scores were 12% (Model 1) to 15% (Models 2 and 3) more likely to have overweight/obesity vs those with lower stress scores, yet not statistically significant. There was no evidence of an association among women (Table 1). Conclusion: Over 80% of both women and men reporting higher stress had overweight/obesity vs those with lower stress score, though not statistically significant. These findings support opportunities to address health behaviors, depression, and psychosocial stress among Black adults in rural communities.

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Cite This Study

Miles et al. (2026) conducted a cross-sectional in Overweight/obesity (n=344). Moderate/high perceived stress vs. Low perceived stress was evaluated on Overweight/obesity (BMI > 25 kg/m2) (PR 1.12-1.15, p=not statistically significant). Moderate to high perceived stress was associated with a 12% to 15% higher prevalence of overweight or obesity among Black men compared to low stress, though not statistically significant.

synapsesocial.com/papers/69fadad703f892aec9b1e722https://doi.org/10.1161/cir.153.suppl_1.th945
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