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May 7, 2026Journal of Intensive Care Medicine0 citations

Prognostic Value of Scoring Systems in Elderly Sepsis-Associated AKI Patients: A Multicenter Retrospective Cohort Study

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HWH X WangNLNahui LiSYSin Yang

Key Points

  • To evaluate the prognostic value of various scoring systems in predicting mortality in elderly patients with sepsis-associated acute kidney injury (AKI).
  • Multicenter retrospective cohort study
  • Assessment of MELD, Charlson, SAPS II, and SAPS III scores
  • Decision curve analysis applied for predictive utility comparison
  • SAPS II showed the strongest AUC (0.789) for 90-day mortality
  • All scoring systems had higher specificity than sensitivity in the dataset
  • Urinary tract infection linked to increased mortality but with limited predictive capacity

Abstract

65) than sensitivity values in our dataset. Furthermore, while urinary tract infection was associated with increased mortality in elderly AKI patients, our subsequent analysis demonstrated its limited predictive capacity for 28-day and 90-day mortality outcomes.ConclusionIn our cohort of elderly sepsis-AKI patients, SAPS II demonstrated the strongest observed prognostic performance for both 28- and 90-day mortality compared to MELD, LODS, and Charlson scores. These findings suggest SAPS II may be valuable for risk stratification in clinical decision-making for this high-risk population, though further validation is warranted.

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Cite This Study

Wang et al. (2026) studied this question.

synapsesocial.com/papers/69fbe3ca164b5133a91a31a5https://doi.org/10.1177/08850666261446564
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