PulseExploreJournal ClubDebatesTrendingResearchersJournals
Instagram
HomeExploreJournal ClubTrending
Synapse
⌘+K
Synapse
May 7, 2026Children0 citationsOpen Access

Lung-Protective Effect of Alveolar Recruitment Maneuvers in Children with Right Vertical Infra-Axillary Thoracotomy for Repair of Congenital Heart Disease

View Full Paper
LZLiang ZhangCWC B WangCHChen He

Key Points

  • This research aims to determine the impact of alveolar recruitment maneuvers on lung function in children undergoing heart surgery.
  • Randomised trial involving children with congenital heart defects corrected via right vertical infra-axillary thoracotomy.
  • Children were split into two groups: one receiving alveolar recruitment maneuver and the other receiving standard care.
  • Pre-and post-surgery measures of lung compliance and oxygenation were compared.
  • Significant improvements in lung oxygenation measured as PaO2 and PaO2/FiO2 in the ARM group versus controls.
  • Lower levels of IL-6 were observed in the ARM group, indicating reduced inflammation.
  • The ARM group experienced fewer incidents of lung injury and atelectasis compared to the control group.

Abstract

Background/Objectives: Right vertical infra-axillary thoracotomy to repair ventricular septal defects (VSDs) and atrial septal defects (ASDs) is less invasive than conventional surgical repair via median sternotomy. However, right vertical infra-axillary thoracotomy (RVIAT) may result in unilateral lung injury, a serious postoperative complication requiring extracorporeal circulation and unilateral lung collapse. The aim of this study was to evaluate whether repeated lung recruitment provides enhanced respiratory compliance and lung oxygenation in children who have undergone right vertical infra-axillary thoracotomy (RVIAT) to correct a congenital heart defect. Methods: Eligible participants were children with a common congenital heart defect corrected via RVIAT. Seventy-seven children were randomly classified into two groups. In group A (n = 39), an alveolar recruitment maneuver (ARM) was performed immediately after cardiopulmonary bypass. Children in group C (n = 38) did not receive any additional interventions during surgery. Results: The ARM group tolerated open lung ventilation without significant hemodynamic instability. Compared to controls, intraoperative PaO2, PaO2/FiO2 and lung compliance (Comdyn) improved in group A (p < 0.05), who also showed a significantly lower IL-6 (p < 0.05). In addition, group A had a lower incidence of lung injury and lung atelectasis than Group C at specific post CPB time points. Conclusions: Our findings provide some indication that the application of ARM could effectively improve the oxygenation profile, reduce postoperative pulmonary complications, and attenuate the postoperative inflammatory response in children with a common congenital heart defect corrected via the RVIAT technique.

Ask AI
Helpful
Bookmark
Share
View Full Paper

Cite This Study

Zhang et al. (2026) studied this question.

synapsesocial.com/papers/69fbefef164b5133a91a4199https://doi.org/10.3390/children13050588
Ask AI
Helpful
Bookmark
Share
View Full Paper