DEEP-URO RA/LP: DE-Escalation of antibiotic Prophylaxis in UROlogical procedures in Robot-Assisted or Laparoscopic Prostatectomy

DEEP-URO RA/LP (DE-Escalation of antibiotic Prophylaxis in UROlogical Procedures in Robot Assisted or Laparoscopic Prostatectomy) establishes a scalable audit for antimicrobial stewardship in RA/LP, generating multicenter evidence linking antibiotic prophylaxis practices to verifiable 30-day infection outcomes. This initiative identifies de-escalation opportunities by benchmarking against European Centers for Disease Control definitions and World Health Organization AWaRe classification, informing guideline updates, risk-stratified protocols, and institutional quality improvement amid the global antimicrobial resistance crisis. The adaptable DEEP-URO framework enables future modules across urologic and surgical specialties, advancing data-driven patient safety while curbing unnecessary antibiotic exposure.